TY - GEN AU - Ding,Kun AU - Eaton,Lucia AU - Bowley,Diana AU - Rieser,Matthew AU - Chang,Qing AU - Harris,Maria C AU - Clabbers,Anca AU - Dong,Feng AU - Shen,Jikui AU - Hackett,Sean F AU - Touw,Debra S AU - Bixby,Jacqueline AU - Zhong,Suju AU - Benatuil,Lorenzo AU - Bose,Sahana AU - Grinnell,Christine AU - Preston,Gregory M AU - Iyer,Ramesh AU - Sadhukhan,Ramkrishna AU - Marchie,Susan AU - Overmeyer,Gary AU - Ghayur,Tariq AU - van Riet,Deborah A AU - Tang,Shibo AU - Campochario,Peter A AU - Gu,Jijie TI - Generation and characterization of ABBV642, a dual variable domain immunoglobulin molecule (DVD-Ig) that potently neutralizes VEGF and PDGF-BB and is designed for the treatment of exudative age-related macular degeneration SN - 1942-0870 PY - 2017///1128 KW - Angiogenesis Inhibitors KW - pharmacology KW - Animals KW - Antibodies, Bispecific KW - Becaplermin KW - Female KW - Humans KW - Macular Degeneration KW - drug therapy KW - Male KW - Mice KW - Mice, Transgenic KW - Protein Engineering KW - Proto-Oncogene Proteins c-sis KW - antagonists & inhibitors KW - Rabbits KW - Vascular Endothelial Growth Factor A N1 - Publication Type: Journal Article UR - https://doi.org/10.1080/19420862.2016.1268305 ER -