Ding, Kun

Generation and characterization of ABBV642, a dual variable domain immunoglobulin molecule (DVD-Ig) that potently neutralizes VEGF and PDGF-BB and is designed for the treatment of exudative age-related macular degeneration. [electronic resource] - mAbs - 269-284 p. digital

Publication Type: Journal Article

1942-0870

10.1080/19420862.2016.1268305 doi


Angiogenesis Inhibitors--pharmacology
Animals
Antibodies, Bispecific--pharmacology
Becaplermin
Female
Humans
Macular Degeneration--drug therapy
Male
Mice
Mice, Transgenic
Protein Engineering
Proto-Oncogene Proteins c-sis--antagonists & inhibitors
Rabbits
Vascular Endothelial Growth Factor A--antagonists & inhibitors