TY  - GEN
AU  - Cao,Juxiang
AU  - Tyburczy,Magdalena E
AU  - Moss,Joel
AU  - Darling,Thomas N
AU  - Widlund,Hans R
AU  - Kwiatkowski,David J
TI  - Tuberous sclerosis complex inactivation disrupts melanogenesis via mTORC1 activation
SN  - 1558-8238
PY  - 2017///0906
KW  - Adolescent
KW  - Adult
KW  - Alleles
KW  - Cell Line, Tumor
KW  - Female
KW  - Glycogen Synthase Kinase 3 beta
KW  - genetics
KW  - Humans
KW  - Male
KW  - Mechanistic Target of Rapamycin Complex 1
KW  - Melanins
KW  - biosynthesis
KW  - Melanocytes
KW  - metabolism
KW  - Microphthalmia-Associated Transcription Factor
KW  - Middle Aged
KW  - Multiprotein Complexes
KW  - Mutation
KW  - Proto-Oncogene Proteins c-akt
KW  - Signal Transduction
KW  - Skin Pigmentation
KW  - TOR Serine-Threonine Kinases
KW  - Tuberous Sclerosis
KW  - Tuberous Sclerosis Complex 1 Protein
KW  - Tuberous Sclerosis Complex 2 Protein
KW  - Tumor Suppressor Proteins
KW  - beta Catenin
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1172/JCI84262
ER  -