Pathological concentration of zinc dramatically accelerates abnormal aggregation of full-length human Tau and thereby significantly increases Tau toxicity in neuronal cells. [electronic resource]
- Biochimica et biophysica acta. Molecular basis of disease 02 2017
- 414-427 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0925-4439
10.1016/j.bbadis.2016.11.022 doi
Alzheimer Disease--metabolism Apoptosis Cations, Divalent--metabolism Cell Line Humans Neurons--metabolism Protein Aggregates Protein Aggregation, Pathological--metabolism Zinc--metabolism tau Proteins--metabolism