Carter-Cooper, Brandon A <br/><br/>
Synthesis, characterization and antineoplastic activity of bis-aziridinyl dimeric naphthoquinone - A novel class of compounds with potent activity against acute myeloid leukemia cells.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  01 2017 
 - 6-10 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural 
<br/><br/><label>ISSN: </label>1464-3405 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2016.11.045  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--chemical synthesis<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>DNA Breaks, Double-Stranded--drug effects<br/>Dose-Response Relationship, Drug<br/>Drug Screening Assays, Antitumor<br/>Humans<br/>Leukemia, Myeloid, Acute--drug therapy<br/>Mice<br/>Mice, Inbred NOD<br/>Molecular Structure<br/>Naphthoquinones--chemical synthesis<br/>Neoplasms, Experimental--drug therapy<br/>Reactive Oxygen Species--metabolism<br/>Structure-Activity Relationship