Zhao, Haijun <br/><br/>
Low dose triptolide reverses chemoresistance in adult acute lymphoblastic leukemia cells via reactive oxygen species generation and DNA damage response disruption.  [electronic resource] 

 -  Oncotarget  Dec 2016 
 - 85515-85528 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1949-2553 
<br/><br/><label>Standard No.: </label>10.18632/oncotarget.13454  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adolescent<br/>Adult<br/>Aged<br/>Animals<br/>Antimetabolites, Antineoplastic--pharmacology<br/>Antineoplastic Agents, Alkylating--pharmacology<br/>Apoptosis--drug effects<br/>Caspase 9--metabolism<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Checkpoint Kinase 1--metabolism<br/>Checkpoint Kinase 2--metabolism<br/>Cytarabine--pharmacology<br/>DNA Damage<br/>Diterpenes--pharmacology<br/>Dose-Response Relationship, Drug<br/>Doxorubicin--pharmacology<br/>Drug Resistance, Multiple--drug effects<br/>Drug Resistance, Neoplasm--drug effects<br/>Epoxy Compounds--pharmacology<br/>Female<br/>Histones--metabolism<br/>Humans<br/>Inhibitory Concentration 50<br/>Male<br/>Membrane Potential, Mitochondrial--drug effects<br/>Mice, Inbred NOD<br/>Mice, SCID<br/>Middle Aged<br/>Oxidative Stress--drug effects<br/>Phenanthrenes--pharmacology<br/>Precursor Cell Lymphoblastic Leukemia-Lymphoma--drug therapy<br/>Reactive Oxygen Species--metabolism<br/>Signal Transduction--drug effects<br/>Tumor Cells, Cultured<br/>Xenograft Model Antitumor Assays<br/>Young Adult