TY  - GEN
AU  - Reuther,Clemens
AU  - Heinzle,Vera
AU  - Nölting,Svenja
AU  - Herterich,Sabine
AU  - Hahner,Stefanie
AU  - Halilovic,Ensar
AU  - Jeay,Sébastien
AU  - Wuerthner,Jens U
AU  - Aristizabal Prada,Elke Tatjana
AU  - Spöttl,Gerald
AU  - Maurer,Julian
AU  - Auernhammer,Christoph J
TI  - The HDM2 (MDM2) Inhibitor NVP-CGM097 Inhibits Tumor Cell Proliferation and Shows Additive Effects with 5-Fluorouracil on the p53-p21-Rb-E2F1 Cascade in the p53wild type Neuroendocrine Tumor Cell Line GOT1
SN  - 1423-0194
PY  - 2019///0103
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - drug effects
KW  - Cyclin-Dependent Kinase Inhibitor p21
KW  - metabolism
KW  - Dose-Response Relationship, Drug
KW  - Drug Resistance, Neoplasm
KW  - Drug Therapy, Combination
KW  - E2F1 Transcription Factor
KW  - Fluorouracil
KW  - Humans
KW  - Isoquinolines
KW  - Neuroendocrine Tumors
KW  - drug therapy
KW  - Piperazines
KW  - Proto-Oncogene Proteins c-mdm2
KW  - antagonists & inhibitors
KW  - Retinoblastoma Protein
KW  - Signal Transduction
KW  - Tumor Suppressor Protein p53
KW  - genetics
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1159/000453369
ER  -