Reuther, Clemens <br/><br/>
The HDM2 (MDM2) Inhibitor NVP-CGM097 Inhibits Tumor Cell Proliferation and Shows Additive Effects with 5-Fluorouracil on the p53-p21-Rb-E2F1 Cascade in the p53wild type Neuroendocrine Tumor Cell Line GOT1.  [electronic resource] 

 -  Neuroendocrinology  2018 
 - 1-19 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1423-0194 
<br/><br/><label>Standard No.: </label>10.1159/000453369  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--pharmacology<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Cyclin-Dependent Kinase Inhibitor p21--metabolism<br/>Dose-Response Relationship, Drug<br/>Drug Resistance, Neoplasm<br/>Drug Therapy, Combination<br/>E2F1 Transcription Factor--metabolism<br/>Fluorouracil--pharmacology<br/>Humans<br/>Isoquinolines--pharmacology<br/>Neuroendocrine Tumors--drug therapy<br/>Piperazines--pharmacology<br/>Proto-Oncogene Proteins c-mdm2--antagonists & inhibitors<br/>Retinoblastoma Protein--metabolism<br/>Signal Transduction--drug effects<br/>Tumor Suppressor Protein p53--genetics