TY  - GEN
AU  - Gazova,Zuzana
AU  - Soukup,Ondrej
AU  - Sepsova,Vendula
AU  - Siposova,Katarina
AU  - Drtinova,Lucie
AU  - Jost,Petr
AU  - Spilovska,Katarina
AU  - Korabecny,Jan
AU  - Nepovimova,Eugenie
AU  - Fedunova,Diana
AU  - Horak,Martin
AU  - Kaniakova,Martina
AU  - Wang,Ze-Jun
AU  - Hamouda,Ayman K
AU  - Kuca,Kamil
TI  - Multi-target-directed therapeutic potential of 7-methoxytacrine-adamantylamine heterodimers in the Alzheimer's disease treatment
SN  - 0925-4439
PY  - 2018///1211
KW  - Alzheimer Disease
KW  - drug therapy
KW  - Amantadine
KW  - analogs & derivatives
KW  - Amyloid Precursor Protein Secretases
KW  - antagonists & inhibitors
KW  - Amyloid beta-Peptides
KW  - Animals
KW  - CHO Cells
KW  - Cholinesterases
KW  - metabolism
KW  - Cricetulus
KW  - Dimerization
KW  - Enzyme Inhibitors
KW  - chemistry
KW  - HEK293 Cells
KW  - Humans
KW  - Molecular Targeted Therapy
KW  - Receptor, Muscarinic M1
KW  - Receptors, Cholinergic
KW  - Receptors, N-Methyl-D-Aspartate
KW  - Tacrine
KW  - Xenopus
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.bbadis.2016.11.020
ER  -