Guryanova, Olga A

DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling. [electronic resource] - Nature medicine 12 2016 - 1488-1495 p. digital

Publication Type: Journal Article

1546-170X

10.1038/nm.4210 doi


Animals
Anthracyclines--therapeutic use
Antineoplastic Agents--therapeutic use
Cell Line, Tumor
Cell Proliferation--genetics
Cell Survival
Chromatin Assembly and Disassembly--genetics
DNA (Cytosine-5-)-Methyltransferases--genetics
DNA Methyltransferase 3A
Daunorubicin--therapeutic use
Drug Resistance, Neoplasm--genetics
Hematopoietic Stem Cells
Humans
Immunoblotting
Immunoprecipitation
Leukemia, Myeloid, Acute--drug therapy
Mass Spectrometry
Mice
Mutation
Nuclear Proteins--genetics
Nucleophosmin
Nucleosomes--metabolism
fms-Like Tyrosine Kinase 3--genetics