TY - GEN AU - Abu Lila,Amr S AU - Moriyoshi,Naoto AU - Fukushima,Masakazu AU - Huang,Cheng-Long AU - Wada,Hiromi AU - Ishida,Tatsuhiro TI - Metronomic S-1 dosing and thymidylate synthase silencing have synergistic antitumor efficacy in a colorectal cancer xenograft model SN - 1872-7980 PY - 2017///0825 KW - Administration, Metronomic KW - Animals KW - Antimetabolites, Antineoplastic KW - administration & dosage KW - Apoptosis KW - drug effects KW - Cell Line, Tumor KW - Cell Proliferation KW - Colorectal Neoplasms KW - enzymology KW - Drug Combinations KW - Humans KW - Male KW - Mice, Inbred BALB C KW - Mice, Nude KW - Oxonic Acid KW - RNA Interference KW - RNAi Therapeutics KW - methods KW - Tegafur KW - Thymidylate Synthase KW - genetics KW - Time Factors KW - Transfection KW - Tumor Burden KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.canlet.2016.11.005 ER -