Abu Lila, Amr S <br/><br/>
Metronomic S-1 dosing and thymidylate synthase silencing have synergistic antitumor efficacy in a colorectal cancer xenograft model.  [electronic resource] 

 -  Cancer letters  08 2017 
 - 223-231 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1872-7980 
<br/><br/><label>Standard No.: </label>10.1016/j.canlet.2016.11.005  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Administration, Metronomic<br/>Animals<br/>Antimetabolites, Antineoplastic--administration & dosage<br/>Apoptosis--drug effects<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Colorectal Neoplasms--enzymology<br/>Drug Combinations<br/>Humans<br/>Male<br/>Mice, Inbred BALB C<br/>Mice, Nude<br/>Oxonic Acid--administration & dosage<br/>RNA Interference<br/>RNAi Therapeutics--methods<br/>Tegafur--administration & dosage<br/>Thymidylate Synthase--genetics<br/>Time Factors<br/>Transfection<br/>Tumor Burden--drug effects<br/>Xenograft Model Antitumor Assays