TY  - GEN
AU  - Roel,María
AU  - Rubiolo,Juan A
AU  - Guerra-Varela,Jorge
AU  - Silva,Siguara B L
AU  - Thomas,Olivier P
AU  - Cabezas-Sainz,Pablo
AU  - Sánchez,Laura
AU  - López,Rafael
AU  - Botana,Luis M
TI  - Marine guanidine alkaloids crambescidins inhibit tumor growth and activate intrinsic apoptotic signaling inducing tumor regression in a colorectal carcinoma zebrafish xenograft model
SN  - 1949-2553
PY  - 2018///0221
KW  - Alkaloids
KW  - pharmacology
KW  - Animals
KW  - Antineoplastic Agents
KW  - Apoptosis
KW  - drug effects
KW  - Caspase 3
KW  - metabolism
KW  - Cell Adhesion
KW  - Cell Cycle Proteins
KW  - Cell Proliferation
KW  - Cell Survival
KW  - Colorectal Neoplasms
KW  - drug therapy
KW  - Cytoskeleton
KW  - Dose-Response Relationship, Drug
KW  - G1 Phase Cell Cycle Checkpoints
KW  - Guanidine
KW  - analogs & derivatives
KW  - HT29 Cells
KW  - Hep G2 Cells
KW  - Humans
KW  - Inhibitory Concentration 50
KW  - MCF-7 Cells
KW  - Membrane Potential, Mitochondrial
KW  - Signal Transduction
KW  - Spiro Compounds
KW  - Time Factors
KW  - Tumor Burden
KW  - Xenograft Model Antitumor Assays
KW  - Zebrafish
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.18632/oncotarget.13068
ER  -