TY  - GEN
AU  - Dever,Daniel P
AU  - Bak,Rasmus O
AU  - Reinisch,Andreas
AU  - Camarena,Joab
AU  - Washington,Gabriel
AU  - Nicolas,Carmencita E
AU  - Pavel-Dinu,Mara
AU  - Saxena,Nivi
AU  - Wilkens,Alec B
AU  - Mantri,Sruthi
AU  - Uchida,Nobuko
AU  - Hendel,Ayal
AU  - Narla,Anupama
AU  - Majeti,Ravindra
AU  - Weinberg,Kenneth I
AU  - Porteus,Matthew H
TI  - CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells
SN  - 1476-4687
PY  - 2017///0321
KW  - Alleles
KW  - Anemia, Sickle Cell
KW  - genetics
KW  - Animals
KW  - Antigens, CD34
KW  - metabolism
KW  - CRISPR-Associated Proteins
KW  - CRISPR-Cas Systems
KW  - Cell Differentiation
KW  - Cell Lineage
KW  - Cell Separation
KW  - Dependovirus
KW  - Erythrocytes
KW  - Female
KW  - Flow Cytometry
KW  - Gene Editing
KW  - methods
KW  - Gene Targeting
KW  - Genes, Reporter
KW  - Genetic Therapy
KW  - Hematopoietic Stem Cells
KW  - Homologous Recombination
KW  - Humans
KW  - Magnets
KW  - Mice, Inbred NOD
KW  - Mice, SCID
KW  - Microspheres
KW  - Mutation
KW  - RNA, Messenger
KW  - biosynthesis
KW  - beta-Globins
KW  - beta-Thalassemia
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/nature20134
ER  -