TY - GEN AU - Zhang,Jingfang AU - Kong,Guangyao AU - Rajagopalan,Adhithi AU - Lu,Li AU - Song,Jingming AU - Hussaini,Mohamed AU - Zhang,Xinmin AU - Ranheim,Erik A AU - Liu,Yangang AU - Wang,Jinyong AU - Gao,Xin AU - Chang,Yuan-I AU - Johnson,Kirby D AU - Zhou,Yun AU - Yang,David AU - Bhatnagar,Bhavana AU - Lucas,David M AU - Bresnick,Emery H AU - Zhong,Xuehua AU - Padron,Eric AU - Zhang,Jing TI - p53-/- synergizes with enhanced NrasG12D signaling to transform megakaryocyte-erythroid progenitors in acute myeloid leukemia SN - 1528-0020 PY - 2017///0823 KW - Animals KW - Bone Marrow Transplantation KW - Cell Transformation, Neoplastic KW - genetics KW - GTP Phosphohydrolases KW - Humans KW - Leukemia, Myeloid, Acute KW - etiology KW - MAP Kinase Signaling System KW - Megakaryocyte-Erythroid Progenitor Cells KW - pathology KW - Membrane Proteins KW - Mice KW - Mutation KW - Signal Transduction KW - Tumor Suppressor Protein p53 KW - deficiency N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1182/blood-2016-06-719237 ER -