TY - GEN AU - Liang,Ruifang AU - Šumová,Barbora AU - Cordazzo,Cinzia AU - Mallano,Tatjana AU - Zhang,Yun AU - Wohlfahrt,Thomas AU - Dees,Clara AU - Ramming,Andreas AU - Krasowska,Dorota AU - Michalska-Jakubus,Małgorzata AU - Distler,Oliver AU - Schett,Georg AU - Šenolt,Ladislav AU - Distler,Jörg H W TI - The transcription factor GLI2 as a downstream mediator of transforming growth factor-β-induced fibroblast activation in SSc SN - 1468-2060 PY - 2017///0606 KW - Adult KW - Aged KW - Anilides KW - pharmacology KW - Animals KW - Cells, Cultured KW - Collagen Type I KW - genetics KW - Connective Tissue Growth Factor KW - Female KW - Fibroblasts KW - drug effects KW - Fibrosis KW - Gene Knockout Techniques KW - Hedgehog Proteins KW - metabolism KW - Humans KW - Kruppel-Like Transcription Factors KW - antagonists & inhibitors KW - Male KW - Mice KW - Mice, Knockout KW - Mice, Transgenic KW - Middle Aged KW - Plasminogen Activator Inhibitor 1 KW - Protein Serine-Threonine Kinases KW - Pteridines KW - Pulmonary Fibrosis KW - chemically induced KW - Pyridines KW - Pyrimidines KW - RNA, Messenger KW - Receptor, Transforming Growth Factor-beta Type I KW - Receptors, Transforming Growth Factor beta KW - Recombinant Proteins KW - Scleroderma, Systemic KW - Signal Transduction KW - Skin KW - Smad3 Protein KW - Smoothened Receptor KW - Transforming Growth Factor beta KW - Young Adult KW - Zinc Finger Protein Gli2 N1 - Publication Type: Journal Article UR - https://doi.org/10.1136/annrheumdis-2016-209698 ER -