TY  - GEN
AU  - Cholewa,Brian D
AU  - Ndiaye,Mary A
AU  - Huang,Wei
AU  - Liu,Xiaoqi
AU  - Ahmad,Nihal
TI  - Small molecule inhibition of polo-like kinase 1 by volasertib (BI 6727) causes significant melanoma growth delay and regression in vivo
SN  - 1872-7980
PY  - 2017///0808
KW  - Animals
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Apoptosis
KW  - drug effects
KW  - Caspase 3
KW  - metabolism
KW  - Cell Cycle Proteins
KW  - antagonists & inhibitors
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Cyclin-Dependent Kinase Inhibitor p21
KW  - Dose-Response Relationship, Drug
KW  - G2 Phase Cell Cycle Checkpoints
KW  - Humans
KW  - Ki-67 Antigen
KW  - Melanoma
KW  - drug therapy
KW  - Mice, Nude
KW  - Molecular Targeted Therapy
KW  - Mutation
KW  - Protein Kinase Inhibitors
KW  - Protein Serine-Threonine Kinases
KW  - Proto-Oncogene Proteins
KW  - Proto-Oncogene Proteins B-raf
KW  - genetics
KW  - Pteridines
KW  - S Phase Cell Cycle Checkpoints
KW  - Signal Transduction
KW  - Skin Neoplasms
KW  - Time Factors
KW  - Tumor Burden
KW  - Tumor Suppressor Protein p53
KW  - Xenograft Model Antitumor Assays
KW  - Polo-Like Kinase 1
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.canlet.2016.10.025
ER  -