Telliez, Jean-Baptiste <br/><br/>
Discovery of a JAK3-Selective Inhibitor: Functional Differentiation of JAK3-Selective Inhibition over pan-JAK or JAK1-Selective Inhibition.  [electronic resource] 

 -  ACS chemical biology  12 2016 
 - 3442-3451 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1554-8937 
<br/><br/><label>Standard No.: </label>10.1021/acschembio.6b00677  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Arthritis, Experimental--drug therapy<br/>Disease Models, Animal<br/>Drug Discovery<br/>Encephalomyelitis, Autoimmune, Experimental--drug therapy<br/>Humans<br/>Interleukin-10--immunology<br/>Interleukin-1beta--immunology<br/>Janus Kinase 1--antagonists & inhibitors<br/>Janus Kinase 3--antagonists & inhibitors<br/>Macrophages--cytology<br/>Mice<br/>Models, Molecular<br/>Protein Kinase Inhibitors--pharmacokinetics<br/>Pyrimidines--pharmacokinetics<br/>Pyrroles--pharmacokinetics<br/>Rats<br/>Th1 Cells--cytology<br/>Th17 Cells--cytology<br/>Tumor Necrosis Factor-alpha--immunology