TY  - GEN
AU  - Jian,Jinlong
AU  - Tian,Qing-Yun
AU  - Hettinghouse,Aubryanna
AU  - Zhao,Shuai
AU  - Liu,Helen
AU  - Wei,Jianlu
AU  - Grunig,Gabriele
AU  - Zhang,Wujuan
AU  - Setchell,Kenneth D R
AU  - Sun,Ying
AU  - Overkleeft,Herman S
AU  - Chan,Gerald L
AU  - Liu,Chuan-Ju
TI  - Progranulin Recruits HSP70 to β-Glucocerebrosidase and Is Therapeutic Against Gaucher Disease
SN  - 2352-3964
PY  - 2017///0214
KW  - Animals
KW  - Cell Line
KW  - Disease Models, Animal
KW  - Fibroblasts
KW  - drug effects
KW  - Gaucher Disease
KW  - drug therapy
KW  - Glucosylceramidase
KW  - metabolism
KW  - HSP70 Heat-Shock Proteins
KW  - genetics
KW  - Humans
KW  - Intercellular Signaling Peptides and Proteins
KW  - Lysosomal Membrane Proteins
KW  - Lysosomes
KW  - Mice
KW  - Mice, Knockout
KW  - Phenotype
KW  - Progranulins
KW  - Protein Aggregates
KW  - Protein Binding
KW  - Recombinant Proteins
KW  - pharmacology
KW  - Stress, Physiological
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.ebiom.2016.10.010
ER  -