TY  - GEN
AU  - Wu,Fei
AU  - Dai,Xiangpeng
AU  - Gan,Wenjian
AU  - Wan,Lixin
AU  - Li,Min
AU  - Mitsiades,Nicholas
AU  - Wei,Wenyi
AU  - Ding,Qiang
AU  - Zhang,Jinfang
TI  - Prostate cancer-associated mutation in SPOP impairs its ability to target Cdc20 for poly-ubiquitination and degradation
SN  - 1872-7980
PY  - 2017///0808
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Carbamates
KW  - Cdc20 Proteins
KW  - antagonists & inhibitors
KW  - Cullin Proteins
KW  - Cyclopentanes
KW  - Diamines
KW  - Dose-Response Relationship, Drug
KW  - Drug Resistance, Neoplasm
KW  - Enzyme Inhibitors
KW  - HeLa Cells
KW  - Humans
KW  - Male
KW  - Molecular Targeted Therapy
KW  - Mutation
KW  - Nuclear Proteins
KW  - genetics
KW  - Prostatic Neoplasms
KW  - drug therapy
KW  - Protein Interaction Domains and Motifs
KW  - Proteolysis
KW  - Pyrimidines
KW  - Repressor Proteins
KW  - Time Factors
KW  - Transfection
KW  - Ubiquitination
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.canlet.2016.10.021
ER  -