TY  - GEN
AU  - Jang,Jiho
AU  - Park,Sangjun
AU  - Jin Hur,Hye
AU  - Cho,Hyun-Ju
AU  - Hwang,Inhwa
AU  - Pyo Kang,Yun
AU  - Im,Isak
AU  - Lee,Hyunji
AU  - Lee,Eunju
AU  - Yang,Wonsuk
AU  - Kang,Hoon-Chul
AU  - Won Kwon,Sung
AU  - Yu,Je-Wook
AU  - Kim,Dong-Wook
TI  - 25-hydroxycholesterol contributes to cerebral inflammation of X-linked adrenoleukodystrophy through activation of the NLRP3 inflammasome
SN  - 2041-1723
PY  - 2018///0823
KW  - ATP Binding Cassette Transporter, Subfamily D, Member 1
KW  - genetics
KW  - Adrenoleukodystrophy
KW  - chemically induced
KW  - Animals
KW  - Corpus Callosum
KW  - drug effects
KW  - Fibroblasts
KW  - Gene Expression
KW  - Hydroxycholesterols
KW  - metabolism
KW  - Induced Pluripotent Stem Cells
KW  - Inflammasomes
KW  - Inflammation
KW  - Injections, Intraventricular
KW  - Liver X Receptors
KW  - Male
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mice, Knockout
KW  - NLR Family, Pyrin Domain-Containing 3 Protein
KW  - agonists
KW  - Oligodendroglia
KW  - Primary Cell Culture
KW  - Reactive Oxygen Species
KW  - Stereotaxic Techniques
KW  - Steroid Hydroxylases
KW  - deficiency
KW  - White Matter
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/ncomms13129
ER  -