ISG12a inhibits HCV replication and potentiates the anti-HCV activity of IFN-α through activation of the Jak/STAT signaling pathway independent of autophagy and apoptosis. [electronic resource]
- Virus research 01 2017
- 231-239 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1872-7492
10.1016/j.virusres.2016.10.013 doi
Apoptosis--genetics Autophagy--genetics Cell Line Cells, Cultured Gene Expression Hepacivirus--physiology Hepatitis C--genetics Humans Interferon Type I--biosynthesis Interferon-alpha--metabolism Interferon-beta--metabolism Janus Kinases--metabolism Membrane Proteins--genetics STAT Transcription Factors--metabolism Signal Transduction--drug effects Virus Replication