TY - GEN AU - Meek,T D AU - Dayton,B D AU - Metcalf,B W AU - Dreyer,G B AU - Strickler,J E AU - Gorniak,J G AU - Rosenberg,M AU - Moore,M L AU - Magaard,V W AU - Debouck,C TI - Human immunodeficiency virus 1 protease expressed in Escherichia coli behaves as a dimeric aspartic protease SN - 0027-8424 PY - 1989///0428 KW - Aspartic Acid Endopeptidases KW - Binding Sites KW - Centrifugation, Density Gradient KW - Chromatography, Gel KW - Electrophoresis, Polyacrylamide Gel KW - Endopeptidases KW - genetics KW - Epoxy Compounds KW - pharmacology KW - Escherichia coli KW - enzymology KW - Gene Products, gag KW - HIV KW - Hydrogen-Ion Concentration KW - Kinetics KW - Macromolecular Substances KW - Molecular Weight KW - Nitrophenols KW - Oligopeptides KW - metabolism KW - Peptide Fragments KW - Protease Inhibitors KW - Recombinant Proteins KW - Retroviridae Proteins KW - Substrate Specificity N1 - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1073/pnas.86.6.1841 ER -