Wan, Xianxiu <br/><br/>
SIRT1-PGC1α-NFκB Pathway of Oxidative and Inflammatory Stress during Trypanosoma cruzi Infection: Benefits of SIRT1-Targeted Therapy in Improving Heart Function in Chagas Disease.  [electronic resource] 

 -  PLoS pathogens  Oct 2016 
 - e1005954 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1553-7374 
<br/><br/><label>Standard No.: </label>10.1371/journal.ppat.1005954  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antioxidants--pharmacology<br/>Blotting, Western<br/>Chagas Cardiomyopathy--metabolism<br/>Disease Models, Animal<br/>Heart--drug effects<br/>Heterocyclic Compounds, 4 or More Rings--pharmacology<br/>Humans<br/>Inflammation--metabolism<br/>Mice<br/>Mice, Inbred C57BL<br/>NF-kappa B--drug effects<br/>Oxidative Stress--drug effects<br/>Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha--drug effects<br/>Resveratrol<br/>Signal Transduction--physiology<br/>Sirtuin 1--drug effects<br/>Stilbenes--pharmacology<br/>Transcriptome<br/>Trypanosoma cruzi