TY - GEN AU - Jan,Asad AU - Jansonius,Brandon AU - Delaidelli,Alberto AU - Somasekharan,Syam Prakash AU - Bhanshali,Forum AU - Vandal,Milène AU - Negri,Gian Luca AU - Moerman,Don AU - MacKenzie,Ian AU - Calon,Frédéric AU - Hayden,Michael R AU - Taubert,Stefan AU - Sorensen,Poul H TI - eEF2K inhibition blocks Aβ42 neurotoxicity by promoting an NRF2 antioxidant response SN - 1432-0533 PY - 2017///0922 KW - Alzheimer Disease KW - enzymology KW - Amyloid beta-Peptides KW - genetics KW - Animals KW - Animals, Genetically Modified KW - Caenorhabditis elegans KW - Cell Survival KW - drug effects KW - Cells, Cultured KW - Elongation Factor 2 Kinase KW - antagonists & inhibitors KW - Enzyme Inhibitors KW - pharmacology KW - Female KW - Frontal Lobe KW - Hippocampus KW - Humans KW - Kelch-Like ECH-Associated Protein 1 KW - metabolism KW - Male KW - NF-E2-Related Factor 2 KW - Neurons KW - Neuroprotective Agents KW - Oxidative Stress KW - Peptide Fragments KW - Reactive Oxygen Species N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1007/s00401-016-1634-1 ER -