Jan, Asad

eEF2K inhibition blocks Aβ42 neurotoxicity by promoting an NRF2 antioxidant response. [electronic resource] - Acta neuropathologica 01 2017 - 101-119 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1432-0533

10.1007/s00401-016-1634-1 doi


Alzheimer Disease--enzymology
Amyloid beta-Peptides--genetics
Animals
Animals, Genetically Modified
Caenorhabditis elegans
Cell Survival--drug effects
Cells, Cultured
Elongation Factor 2 Kinase--antagonists & inhibitors
Enzyme Inhibitors--pharmacology
Female
Frontal Lobe--drug effects
Hippocampus--drug effects
Humans
Kelch-Like ECH-Associated Protein 1--metabolism
Male
NF-E2-Related Factor 2--metabolism
Neurons--drug effects
Neuroprotective Agents--pharmacology
Oxidative Stress--drug effects
Peptide Fragments--genetics
Reactive Oxygen Species