Chen, Minghui <br/><br/>
Apigenin potentiates TRAIL therapy of non-small cell lung cancer via upregulating DR4/DR5 expression in a p53-dependent manner.  [electronic resource] 

 -  Scientific reports  10 2016 
 - 35468 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>2045-2322 
<br/><br/><label>Standard No.: </label>10.1038/srep35468  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Apigenin--pharmacology<br/>Apoptosis--drug effects<br/>Carcinoma, Non-Small-Cell Lung--genetics<br/>Caspases--metabolism<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Disease Models, Animal<br/>Drug Synergism<br/>Gene Expression Regulation, Neoplastic--drug effects<br/>Humans<br/>Lung Neoplasms--genetics<br/>MAP Kinase Signaling System<br/>Mice<br/>Mitochondria--drug effects<br/>NF-kappa B--metabolism<br/>Phosphatidylinositol 3-Kinases--metabolism<br/>Proto-Oncogene Proteins c-akt--metabolism<br/>Receptors, TNF-Related Apoptosis-Inducing Ligand--genetics<br/>Signal Transduction--drug effects<br/>TNF-Related Apoptosis-Inducing Ligand--pharmacology<br/>Tumor Stem Cell Assay<br/>Tumor Suppressor Protein p53--metabolism<br/>Xenograft Model Antitumor Assays