Chen, Yi-Hsuan <br/><br/>
Chemical Inhibition of Human Thymidylate Kinase and Structural Insights into the Phosphate Binding Loop and Ligand-Induced Degradation.  [electronic resource] 

 -  Journal of medicinal chemistry  11 2016 
 - 9906-9918 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/acs.jmedchem.6b01280  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Binding Sites--drug effects<br/>Calorimetry<br/>Cell Line<br/>Cell Survival--drug effects<br/>Crystallography, X-Ray<br/>Dose-Response Relationship, Drug<br/>Humans<br/>Mice<br/>Models, Molecular<br/>Molecular Structure<br/>Nucleoside-Phosphate Kinase--antagonists & inhibitors<br/>Phosphates--metabolism<br/>Protein Kinase Inhibitors--chemical synthesis<br/>Proteolysis--drug effects<br/>Structure-Activity Relationship