TY - GEN AU - Dirix,Luc AU - Swaisland,Helen AU - Verheul,Henk M W AU - Rottey,Sylvie AU - Leunen,Karin AU - Jerusalem,Guy AU - Rolfo,Christian AU - Nielsen,Dorte AU - Molife,L Rhoda AU - Kristeleit,Rebecca AU - Vos-Geelen,Judith de AU - Mau-Sørensen,Morten AU - Soetekouw,Patricia AU - van Herpen,Carla AU - Fielding,Anitra AU - So,Karen AU - Bannister,Wendy AU - Plummer,Ruth TI - Effect of Itraconazole and Rifampin on the Pharmacokinetics of Olaparib in Patients With Advanced Solid Tumors: Results of Two Phase I Open-label Studies SN - 1879-114X PY - 2017///0928 KW - Adult KW - Aged KW - Aged, 80 and over KW - Antineoplastic Agents KW - administration & dosage KW - Area Under Curve KW - Cytochrome P-450 CYP3A Inhibitors KW - pharmacology KW - Cytochrome P-450 Enzyme System KW - drug effects KW - Female KW - Humans KW - Itraconazole KW - Male KW - Middle Aged KW - Neoplasms KW - drug therapy KW - Phthalazines KW - Piperazines KW - Rifampin N1 - Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study UR - https://doi.org/10.1016/j.clinthera.2016.08.010 ER -