TY - GEN AU - Gaiotto,Tiziano AU - Hufton,Simon E TI - Cross-Neutralising Nanobodies Bind to a Conserved Pocket in the Hemagglutinin Stem Region Identified Using Yeast Display and Deep Mutational Scanning SN - 1932-6203 PY - 2017///0522 KW - Amino Acid Sequence KW - Antibodies, Monoclonal KW - immunology KW - Antibodies, Neutralizing KW - Antigen-Antibody Reactions KW - Epitope Mapping KW - Epitopes KW - Hemagglutinin Glycoproteins, Influenza Virus KW - genetics KW - Humans KW - Hydrogen-Ion Concentration KW - Influenza A Virus, H1N1 Subtype KW - metabolism KW - Molecular Sequence Data KW - Mutagenesis KW - Peptide Library KW - Protein Structure, Tertiary KW - Saccharomyces cerevisiae KW - Sequence Analysis, DNA KW - Single-Domain Antibodies KW - Surface Plasmon Resonance KW - Temperature N1 - Publication Type: Journal Article UR - https://doi.org/10.1371/journal.pone.0164296 ER -