TY  - GEN
AU  - Uy,G L
AU  - Duncavage,E J
AU  - Chang,G S
AU  - Jacoby,M A
AU  - Miller,C A
AU  - Shao,J
AU  - Heath,S
AU  - Elliott,K
AU  - Reineck,T
AU  - Fulton,R S
AU  - Fronick,C C
AU  - O'Laughlin,M
AU  - Ganel,L
AU  - Abboud,C N
AU  - Cashen,A F
AU  - DiPersio,J F
AU  - Wilson,R K
AU  - Link,D C
AU  - Welch,J S
AU  - Ley,T J
AU  - Graubert,T A
AU  - Westervelt,P
AU  - Walter,M J
TI  - Dynamic changes in the clonal structure of MDS and AML in response to epigenetic therapy
SN  - 1476-5551
PY  - 2017///1009
KW  - Aged
KW  - Aged, 80 and over
KW  - Antineoplastic Combined Chemotherapy Protocols
KW  - therapeutic use
KW  - Bone Marrow
KW  - pathology
KW  - Clonal Evolution
KW  - genetics
KW  - Epigenesis, Genetic
KW  - drug effects
KW  - Exome
KW  - Female
KW  - Genes, p53
KW  - High-Throughput Nucleotide Sequencing
KW  - Histone Deacetylase Inhibitors
KW  - administration & dosage
KW  - Humans
KW  - Leukemia, Myeloid, Acute
KW  - diagnosis
KW  - Male
KW  - Middle Aged
KW  - Mutation
KW  - Myelodysplastic Syndromes
KW  - Polymorphism, Single Nucleotide
KW  - Remission Induction
KW  - Treatment Outcome
KW  - Tumor Burden
N1  - Publication Type: Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1038/leu.2016.282
ER  -