Dynamic changes in the clonal structure of MDS and AML in response to epigenetic therapy. [electronic resource]
- Leukemia 04 2017
- 872-881 p. digital
Publication Type: Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
1476-5551
10.1038/leu.2016.282 doi
Aged Aged, 80 and over Antineoplastic Combined Chemotherapy Protocols--therapeutic use Bone Marrow--pathology Clonal Evolution--genetics Epigenesis, Genetic--drug effects Exome Female Genes, p53 High-Throughput Nucleotide Sequencing Histone Deacetylase Inhibitors--administration & dosage Humans Leukemia, Myeloid, Acute--diagnosis Male Middle Aged Mutation Myelodysplastic Syndromes--diagnosis Polymorphism, Single Nucleotide Remission Induction Treatment Outcome Tumor Burden