TY - GEN AU - Hamedani,Nasim Shahidi AU - Rühl,Heiko AU - Zimmermann,Julia Janina AU - Heiseler,Tim AU - Oldenburg,Johannes AU - Mayer,Günter AU - Pötzsch,Bernd AU - Müller,Jens TI - In Vitro Evaluation of Aptamer-Based Reversible Inhibition of Anticoagulant Activated Protein C as a Novel Supportive Hemostatic Approach SN - 2159-3345 PY - 2017///1110 KW - Anticoagulants KW - chemical synthesis KW - Aptamers, Nucleotide KW - Base Pairing KW - Humans KW - Kinetics KW - Nucleic Acid Conformation KW - Oligonucleotides, Antisense KW - Partial Thromboplastin Time KW - Protein Binding KW - Protein C KW - antagonists & inhibitors KW - Recombinant Proteins KW - chemistry KW - Thermodynamics KW - Thrombin KW - agonists KW - Whole Blood Coagulation Time N1 - Publication Type: Journal Article UR - https://doi.org/10.1089/nat.2016.0645 ER -