TY - GEN AU - Xiao,Hai-Yun AU - Watterson,Scott H AU - Langevine,Charles M AU - Srivastava,Anurag S AU - Ko,Soo S AU - Zhang,Yanlei AU - Cherney,Robert J AU - Guo,Wei-Wei AU - Gilmore,John L AU - Sheppeck,James E AU - Wu,Dauh-Rurng AU - Li,Peng AU - Ramasamy,Duraisamy AU - Arunachalam,Piramanayagam AU - Mathur,Arvind AU - Taylor,Tracy L AU - Shuster,David J AU - McIntyre,Kim W AU - Shen,Ding-Ren AU - Yarde,Melissa AU - Cvijic,Mary Ellen AU - Marino,Anthony M AU - Balimane,Praveen V AU - Yang,Zheng AU - Banas,Dana M AU - Cornelius,Georgia AU - D'Arienzo,Celia J AU - Warrack,Bethanne M AU - Lehman-McKeeman,Lois AU - Salter-Cid,Luisa M AU - Xie,Jenny AU - Barrish,Joel C AU - Carter,Percy H AU - Dyckman,Alaric J AU - Dhar,T G Murali TI - Identification of Tricyclic Agonists of Sphingosine-1-phosphate Receptor 1 (S1P SN - 1520-4804 PY - 2017///0608 KW - Animals KW - Arthritis, Experimental KW - drug therapy KW - Dogs KW - Dose-Response Relationship, Drug KW - Drug Design KW - Fingolimod Hydrochloride KW - administration & dosage KW - Freund's Adjuvant KW - Heterocyclic Compounds, 3-Ring KW - Ligands KW - Lymphocytes KW - drug effects KW - Macaca fascicularis KW - Male KW - Mice KW - Molecular Structure KW - Mycobacterium KW - Rats KW - Rats, Inbred Lew KW - Receptors, Lysosphingolipid KW - agonists KW - Structure-Activity Relationship KW - Tissue Distribution N1 - Publication Type: Journal Article UR - https://doi.org/10.1021/acs.jmedchem.6b01099 ER -