TY  - GEN
AU  - Ma,Yunqing
AU  - Zhang,Jiayuan
AU  - Yin,Weijie
AU  - Zhang,Zhenchao
AU  - Song,Yan
AU  - Chang,Xing
TI  - Targeted AID-mediated mutagenesis (TAM) enables efficient genomic diversification in mammalian cells
SN  - 1548-7105
PY  - 2017///0526
KW  - CRISPR-Associated Proteins
KW  - chemistry
KW  - Cell Culture Techniques
KW  - Clustered Regularly Interspaced Short Palindromic Repeats
KW  - genetics
KW  - Cytidine Deaminase
KW  - Drug Resistance, Neoplasm
KW  - Fusion Proteins, bcr-abl
KW  - Gene Targeting
KW  - Green Fluorescent Proteins
KW  - HEK293 Cells
KW  - Humans
KW  - Imatinib Mesylate
KW  - pharmacology
KW  - K562 Cells
KW  - Mutagenesis, Site-Directed
KW  - Point Mutation
KW  - RNA, Guide, CRISPR-Cas Systems
KW  - Recombinant Fusion Proteins
KW  - AICDA (Activation-Induced Cytidine Deaminase)
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1038/nmeth.4027
ER  -