Kashyap, Trinayan <br/><br/>
Selinexor, a Selective Inhibitor of Nuclear Export (SINE) compound, acts through NF-κB deactivation and combines with proteasome inhibitors to synergistically induce tumor cell death.  [electronic resource] 

 -  Oncotarget  Nov 2016 
 - 78883-78895 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article 
<br/><br/><label>ISSN: </label>1949-2553 
<br/><br/><label>Standard No.: </label>10.18632/oncotarget.12428  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Active Transport, Cell Nucleus--drug effects<br/>Animals<br/>Antineoplastic Combined Chemotherapy Protocols--pharmacology<br/>Bone Neoplasms--drug therapy<br/>Bortezomib--pharmacology<br/>Cell Death--drug effects<br/>Cell Line, Tumor<br/>Cell Nucleus--drug effects<br/>Dose-Response Relationship, Drug<br/>Drug Resistance, Neoplasm<br/>Drug Synergism<br/>Female<br/>Fibrosarcoma--drug therapy<br/>Humans<br/>Hydrazines--pharmacology<br/>Karyopherins--antagonists & inhibitors<br/>Mice, Inbred ICR<br/>Mice, SCID<br/>NF-KappaB Inhibitor alpha--genetics<br/>NF-kappa B--genetics<br/>Osteosarcoma--drug therapy<br/>Phosphorylation<br/>Proteasome Endopeptidase Complex--metabolism<br/>Proteasome Inhibitors--pharmacology<br/>Proteolysis<br/>RNA Interference<br/>Receptors, Cytoplasmic and Nuclear--antagonists & inhibitors<br/>Signal Transduction--drug effects<br/>Time Factors<br/>Transcription Factor RelA--genetics<br/>Transfection<br/>Triazoles--pharmacology<br/>Exportin 1 Protein