Yang, Jianqi RGS6 is an essential tumor suppressor that prevents bladder carcinogenesis by promoting p53 activation and DNMT1 downregulation. [electronic resource] - Oncotarget Oct 2016 - 69159-69172 p. digital Publication Type: Journal Article ISSN: 1949-2553 Standard No.: 10.18632/oncotarget.12473 doi Subjects--Topical Terms: AnimalsButylhydroxybutylnitrosamine--toxicityCell Transformation, Neoplastic--drug effectsDNA (Cytosine-5-)-Methyltransferase 1--geneticsGene Expression--drug effectsHumansMice, Inbred C57BLMice, KnockoutRGS Proteins--geneticsTumor Suppressor Protein p53--geneticsTumor Suppressor Proteins--geneticsUrinary Bladder--drug effectsUrinary Bladder Neoplasms--chemically inducedUrothelium--drug effects