TY  - GEN
AU  - Ramkumar,Kavya
AU  - Samanta,Soma
AU  - Kyani,Anahita
AU  - Yang,Suhui
AU  - Tamura,Shuzo
AU  - Ziemke,Elizabeth
AU  - Stuckey,Jeanne A
AU  - Li,Si
AU  - Chinnaswamy,Krishnapriya
AU  - Otake,Hiroyuki
AU  - Debnath,Bikash
AU  - Yarovenko,Vladimir
AU  - Sebolt-Leopold,Judith S
AU  - Ljungman,Mats
AU  - Neamati,Nouri
TI  - Mechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor
SN  - 2041-1723
PY  - 2018///0910
KW  - Acetamides
KW  - chemistry
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Catalytic Domain
KW  - Cell Line, Tumor
KW  - Cell Movement
KW  - Cell Survival
KW  - Colonic Neoplasms
KW  - drug therapy
KW  - Crystallography, X-Ray
KW  - Cysteine
KW  - Drug Design
KW  - Drug Resistance, Neoplasm
KW  - Endoplasmic Reticulum
KW  - metabolism
KW  - Enzyme Inhibitors
KW  - Gene Silencing
KW  - Glutathione Transferase
KW  - antagonists & inhibitors
KW  - HCT116 Cells
KW  - High-Throughput Nucleotide Sequencing
KW  - Humans
KW  - Neoplasm Transplantation
KW  - Oxidative Stress
KW  - RNA, Small Interfering
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1038/ncomms13084
ER  -