TY - GEN AU - Tam,Hok Hei AU - Melo,Mariane B AU - Kang,Myungsun AU - Pelet,Jeisa M AU - Ruda,Vera M AU - Foley,Maria H AU - Hu,Joyce K AU - Kumari,Sudha AU - Crampton,Jordan AU - Baldeon,Alexis D AU - Sanders,Rogier W AU - Moore,John P AU - Crotty,Shane AU - Langer,Robert AU - Anderson,Daniel G AU - Chakraborty,Arup K AU - Irvine,Darrell J TI - Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination SN - 1091-6490 PY - 2018///0130 KW - AIDS Vaccines KW - administration & dosage KW - Adjuvants, Immunologic KW - Animals KW - Antibodies, Viral KW - biosynthesis KW - Antibody Affinity KW - B-Lymphocytes KW - cytology KW - CHO Cells KW - Cricetulus KW - Drug Administration Schedule KW - Female KW - Germinal Center KW - HEK293 Cells KW - HIV Envelope Protein gp120 KW - Humans KW - Immunogenicity, Vaccine KW - Infusion Pumps, Implantable KW - Lipid A KW - Mice KW - Mice, Inbred C57BL KW - Osmotic Pressure KW - Recombinant Fusion Proteins KW - Vaccination KW - instrumentation N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1073/pnas.1606050113 ER -