TY  - GEN
AU  - Blunt,Matthew D
AU  - Koehrer,Stefan
AU  - Dobson,Rachel C
AU  - Larrayoz,Marta
AU  - Wilmore,Sarah
AU  - Hayman,Alice
AU  - Parnell,Jack
AU  - Smith,Lindsay D
AU  - Davies,Andrew
AU  - Johnson,Peter W M
AU  - Conley,Pamela B
AU  - Pandey,Anjali
AU  - Strefford,Jonathan C
AU  - Stevenson,Freda K
AU  - Packham,Graham
AU  - Forconi,Francesco
AU  - Coffey,Greg P
AU  - Burger,Jan A
AU  - Steele,Andrew J
TI  - The Dual Syk/JAK Inhibitor Cerdulatinib Antagonizes B-cell Receptor and Microenvironmental Signaling in Chronic Lymphocytic Leukemia
SN  - 1557-3265
PY  - 2018///0221
KW  - Adenine
KW  - analogs & derivatives
KW  - Antineoplastic Combined Chemotherapy Protocols
KW  - administration & dosage
KW  - Apoptosis
KW  - drug effects
KW  - B-Lymphocytes
KW  - Bridged Bicyclo Compounds, Heterocyclic
KW  - Flow Cytometry
KW  - Gene Expression Regulation, Neoplastic
KW  - Humans
KW  - Janus Kinase Inhibitors
KW  - Janus Kinases
KW  - antagonists & inhibitors
KW  - Leukemia, Lymphocytic, Chronic, B-Cell
KW  - drug therapy
KW  - Leukocytes, Mononuclear
KW  - Neoplasm Proteins
KW  - genetics
KW  - Piperidines
KW  - Proto-Oncogene Proteins c-bcr
KW  - Pyrazoles
KW  - Pyrimidines
KW  - Receptors, Antigen, B-Cell
KW  - Signal Transduction
KW  - Sulfonamides
KW  - Sulfones
KW  - Syk Kinase
KW  - Tumor Microenvironment
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1158/1078-0432.CCR-16-1662
ER  -