Shi, Fuguo <br/><br/>
NQO1 and CYP450 reductase decrease the systemic exposure of rifampicin-quinone and mediate its redox cycle in rats.  [electronic resource] 

 -  Journal of pharmaceutical and biomedical analysis  Jan 2017 
 - 17-23 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1873-264X 
<br/><br/><label>Standard No.: </label>10.1016/j.jpba.2016.09.040  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Calibration<br/>Chromatography, Liquid<br/>Cytochrome P-450 Enzyme System--metabolism<br/>Hep G2 Cells<br/>Humans<br/>Limit of Detection<br/>Male<br/>Mass Spectrometry<br/>NAD(P)H Dehydrogenase (Quinone)--metabolism<br/>Oxidation-Reduction<br/>Quality Control<br/>Quinones--chemistry<br/>Rats<br/>Rats, Sprague-Dawley<br/>Reactive Oxygen Species--metabolism<br/>Reproducibility of Results<br/>Rifampin--analogs & derivatives<br/>Time Factors