Ingersoll, Matthew A
Statin derivatives as therapeutic agents for castration-resistant prostate cancer. [electronic resource]
- Cancer letters 12 2016
- 94-105 p. digital
Publication Type: Journal Article
1872-7980
10.1016/j.canlet.2016.09.008 doi
Androgen Antagonists--pharmacology
Antineoplastic Agents, Hormonal--pharmacology
Antineoplastic Combined Chemotherapy Protocols--pharmacology
Apoptosis--drug effects
Cell Line, Tumor
Cell Movement--drug effects
Cell Proliferation--drug effects
Cholesterol--metabolism
Docetaxel
Dose-Response Relationship, Drug
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors--pharmacology
Male
Neoplasm Invasiveness
Prostatic Neoplasms, Castration-Resistant--drug therapy
Proto-Oncogene Proteins c-akt--metabolism
Receptors, Androgen--drug effects
S Phase Cell Cycle Checkpoints--drug effects
Signal Transduction--drug effects
Simvastatin--analogs & derivatives
Taxoids--pharmacology