Bufalin inhibits pancreatic cancer by inducing cell cycle arrest via the c-Myc/NF-κB pathway. [electronic resource]
- Journal of ethnopharmacology Dec 2016
- 538-545 p. digital
Publication Type: Journal Article
1872-7573
10.1016/j.jep.2016.09.047 doi
Animals Antineoplastic Agents--pharmacology Bufanolides--pharmacology Cell Cycle Proteins--genetics Cell Line, Tumor Cell Proliferation--drug effects Cisplatin--pharmacology Dose-Response Relationship, Drug Gene Expression Regulation, Neoplastic Genes, Reporter Humans Luciferases--biosynthesis Male Mice, Inbred BALB C Mice, Nude NF-kappa B--genetics Pancreatic Neoplasms--drug therapy Proto-Oncogene Proteins c-myc--genetics S Phase Cell Cycle Checkpoints--drug effects Signal Transduction--drug effects Time Factors Transfection Tumor Burden--drug effects Xenograft Model Antitumor Assays