Higgins, Sarah J <br/><br/>
Dysregulation of angiopoietin-1 plays a mechanistic role in the pathogenesis of cerebral malaria.  [electronic resource] 

 -  Science translational medicine  09 2016 
 - 358ra128 p.  digital 
<br/><br/> Publication Type: Journal Article; Randomized Controlled Trial 
<br/><br/><label>ISSN: </label>1946-6242 
<br/><br/><label>Standard No.: </label>10.1126/scitranslmed.aaf6812  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adenoviridae--metabolism<br/>Angiopoietin-1--metabolism<br/>Animals<br/>Antimalarials--pharmacology<br/>Artemisinins--pharmacology<br/>Artesunate<br/>Blood-Brain Barrier--pathology<br/>Child, Preschool<br/>Disease Models, Animal<br/>Disease Susceptibility<br/>Endothelial Cells--drug effects<br/>Female<br/>Gene Deletion<br/>Humans<br/>Infant<br/>Kaplan-Meier Estimate<br/>Kinetics<br/>Malaria, Cerebral--etiology<br/>Malaria, Falciparum--metabolism<br/>Male<br/>Mice, Inbred C57BL<br/>Phenotype<br/>Plasmodium falciparum--drug effects<br/>Receptor, TIE-2--metabolism<br/>Recombinant Proteins--pharmacology<br/>Survival Analysis<br/>Treatment Outcome<br/>Uganda