TY  - GEN
AU  - Courtin,Aurelie
AU  - Smyth,Tomoko
AU  - Hearn,Keisha
AU  - Saini,Harpreet K
AU  - Thompson,Neil T
AU  - Lyons,John F
AU  - Wallis,Nicola G
TI  - Emergence of resistance to tyrosine kinase inhibitors in non-small-cell lung cancer can be delayed by an upfront combination with the HSP90 inhibitor onalespib
SN  - 1532-1827
PY  - 2017///0523
KW  - Animals
KW  - Antineoplastic Combined Chemotherapy Protocols
KW  - therapeutic use
KW  - Benzamides
KW  - administration & dosage
KW  - Carcinoma, Non-Small-Cell Lung
KW  - drug therapy
KW  - Cell Line, Tumor
KW  - Crizotinib
KW  - Drug Resistance, Neoplasm
KW  - drug effects
KW  - Erlotinib Hydrochloride
KW  - HSP90 Heat-Shock Proteins
KW  - antagonists & inhibitors
KW  - Humans
KW  - Isoindoles
KW  - Lung Neoplasms
KW  - Male
KW  - Mice, Inbred BALB C
KW  - Mice, SCID
KW  - Neoadjuvant Therapy
KW  - methods
KW  - Neoplasm Recurrence, Local
KW  - prevention & control
KW  - Protein Kinase Inhibitors
KW  - Pyrazoles
KW  - Pyridines
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1038/bjc.2016.294
ER  -