Transcriptome analyses demonstrate that Peroxisome Proliferator-Activated Receptor α (PPARα) activity of an ultraviolet absorber, 2-(2'-hydroxy-3',5'-di-tert-butylphenyl)benzotriazole, as possible mechanism of their toxicity and the gender differences. [electronic resource]
- The Journal of toxicological sciences 2016
- 693-700 p. digital
Publication Type: Comparative Study; Letter
1880-3989
10.2131/jts.41.693 doi
Animals Chemical and Drug Induced Liver Injury--etiology Computational Biology Databases, Genetic Female Gene Expression Profiling--methods Gene Expression Regulation, Developmental Liver--drug effects Male Oligonucleotide Array Sequence Analysis PPAR alpha--agonists RNA, Messenger--genetics Rats, Sprague-Dawley Sex Factors Time Factors Triazoles--toxicity