TY  - GEN
AU  - Wang,Rongsheng E
AU  - Wang,Ying
AU  - Zhang,Yuhan
AU  - Gabrelow,Chase
AU  - Zhang,Yong
AU  - Chi,Victor
AU  - Fu,Qiangwei
AU  - Luo,Xiaozhou
AU  - Wang,Danling
AU  - Joseph,Sean
AU  - Johnson,Kristen
AU  - Chatterjee,Arnab K
AU  - Wright,Timothy M
AU  - Nguyen-Tran,Vân T B
AU  - Teijaro,John
AU  - Theofilopoulos,Argyrios N
AU  - Schultz,Peter G
AU  - Wang,Feng
TI  - Rational design of a Kv1.3 channel-blocking antibody as a selective immunosuppressant
SN  - 1091-6490
PY  - 2018///0126
KW  - Amino Acid Sequence
KW  - Animals
KW  - Antibodies, Blocking
KW  - pharmacology
KW  - CHO Cells
KW  - Cattle
KW  - Complementarity Determining Regions
KW  - chemistry
KW  - Cricetinae
KW  - Cricetulus
KW  - Drug Design
KW  - HEK293 Cells
KW  - Humans
KW  - Immunosuppressive Agents
KW  - Kv1.3 Potassium Channel
KW  - antagonists & inhibitors
KW  - Lymphocyte Activation
KW  - drug effects
KW  - Rats
KW  - Recombinant Fusion Proteins
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1073/pnas.1612803113
ER  -