TY - GEN AU - Kuthning,Anja AU - Durkin,Patrick AU - Oehm,Stefan AU - Hoesl,Michael G AU - Budisa,Nediljko AU - Süssmuth,Roderich D TI - Towards Biocontained Cell Factories: An Evolutionarily Adapted Escherichia coli Strain Produces a New-to-nature Bioactive Lantibiotic Containing Thienopyrrole-Alanine SN - 2045-2322 PY - 2018///0604 KW - Adaptation, Physiological KW - Alanine KW - pharmacology KW - Amino Acid Sequence KW - Anti-Infective Agents KW - Bacteriocins KW - Biological Evolution KW - Escherichia coli KW - drug effects KW - Microbial Sensitivity Tests KW - Peptides KW - chemistry KW - Pyrroles KW - Ribosomes KW - metabolism KW - Spectrometry, Mass, Electrospray Ionization N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/srep33447 ER -