TY - GEN AU - Jeganathan,Niranjan AU - Predescu,Dan AU - Zhang,Jin AU - Sha,Fei AU - Bardita,Cristina AU - Patel,Monal AU - Wood,Stephen AU - Borgia,Jeffrey A AU - Balk,Robert A AU - Predescu,Sanda TI - Rac1-mediated cytoskeleton rearrangements induced by intersectin-1s deficiency promotes lung cancer cell proliferation, migration and metastasis SN - 1476-4598 PY - 2017///0728 KW - A549 Cells KW - Adaptor Proteins, Signal Transducing KW - genetics KW - Adaptor Proteins, Vesicular Transport KW - deficiency KW - Animals KW - Cell Line, Tumor KW - Cell Movement KW - Cell Proliferation KW - Gene Expression Regulation, Neoplastic KW - Humans KW - Lung Neoplasms KW - Mice KW - Neoplasm Metastasis KW - Neoplasm Transplantation KW - Proto-Oncogene Proteins c-cbl KW - SOS1 Protein KW - Time-Lapse Imaging KW - Ubiquitination KW - rac1 GTP-Binding Protein N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1186/s12943-016-0543-1 ER -