TY - GEN AU - Suryo Rahmanto,Aldwin AU - Savov,Vasil AU - Brunner,Andrä AU - Bolin,Sara AU - Weishaupt,Holger AU - Malyukova,Alena AU - Rosén,Gabriela AU - Čančer,Matko AU - Hutter,Sonja AU - Sundström,Anders AU - Kawauchi,Daisuke AU - Jones,David Tw AU - Spruck,Charles AU - Taylor,Michael D AU - Cho,Yoon-Jae AU - Pfister,Stefan M AU - Kool,Marcel AU - Korshunov,Andrey AU - Swartling,Fredrik J AU - Sangfelt,Olle TI - FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma SN - 1460-2075 PY - 2017///0717 KW - Aniline Compounds KW - pharmacology KW - Animals KW - Benzamides KW - Cell Cycle Proteins KW - genetics KW - Cell Line, Tumor KW - Cell Movement KW - Chromones KW - Cisplatin KW - F-Box Proteins KW - F-Box-WD Repeat-Containing Protein 7 KW - Glycogen Synthase Kinase 3 KW - metabolism KW - HEK293 Cells KW - Humans KW - Medulloblastoma KW - drug therapy KW - Mice, Nude KW - Morpholines KW - Phosphatidylinositol 3-Kinases KW - Phosphoinositide-3 Kinase Inhibitors KW - Protein Kinase Inhibitors KW - Proto-Oncogene Proteins c-akt KW - antagonists & inhibitors KW - Pyrimidines KW - Pyrroles KW - SOX9 Transcription Factor KW - TOR Serine-Threonine Kinases KW - Ubiquitin-Protein Ligases KW - Ubiquitination N1 - Publication Type: Journal Article UR - https://doi.org/10.15252/embj.201693889 ER -